Table 1 Pathophysiological characteristics of 4C30 and WT mice

From: Wisteria floribunda agglutinin staining for the quantitative assessment of cardiac fibrogenic activity in a mouse model of dilated cardiomyopathy

 

12-week-old

24-week-old

 

WT

4C30

WT

4C30

N

9

9

7

7

HW/BW (%)

0.56 ± 0.05

0.71 ± 0.08*

0.49 ± 0.04

0.83 ± 0.26*

LVDd (mm)

3.33 ± 0.28

4.06 ± 0.42*

3.75 ± 0.23

4.67 ± 0.78*

LVDs (mm)

1.90 ± 0.32

2.90 ± 0.63*

2.34 ± 0.57

4.16 ± 1.09*†

EF (%)

74.8 ± 7.3

55.5 ± 13.7*

66.9 ± 16.5

25.4 ± 18.9*†

FS (%)

43.1 ± 7.3

29.3 ± 10.0*

37.8 ± 12.3

12.2 ± 9.6*†

  1. Data are presented as means ± SD
  2. HW heart weight, BW body weight, LVDd LV end-diastolic dimension, LVDs LV end-systolic dimension,
  3. EF ejection fraction, FS fractional shortening
  4. *P < 0.05 between 4C30 and age-matched WT mice
  5. †P < 0.05 between 4C30 mice at 12 and 24 weeks
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