Fig. 5 | Laboratory Investigation

Fig. 5

From: Differential engagement of ORAI1 and TRPC1 in the induction of vimentin expression by different stimuli

Fig. 5

YM58483-mediated pharmacological inhibition of store-operated calcium entry in MDA-MB-468 cells. a Average relative [Ca2+]CYT transients and b ratio of Peak 2/Peak 1 (maximum peak height, as indicated in panel (A)) in MDA-MB-468 cells pretreated (15 min) with increasing concentrations of the store-operated Ca2+ entry inhibitor, YM58483. Inhibitor concentrations were maintained for the duration of the experiment (1200 s). Bar graphs represent the mean ± SD for three independent experiments. P < 0.05 (one-way ANOVA with Tukey’s multiple comparisons test)

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