Fig. 4 | Laboratory Investigation

Fig. 4

From: Retinoid-related orphan nuclear receptor alpha (RORα)-deficient mice display morphological testicular defects

Fig. 4

Semithin sections of the interstitial tissues of control and mutant mice stained with toluidine blue. a WT mice show seminiferous tubules (ST) surrounded by myoid cells (arrowheads). The interstitial tissue was composed of Leydig cells (LC), lymphocytes (L), and macrophages (M). b, c Telocytes (arrowheads) were spindle-shaped dark cells distributed around the tubules and blood vessels. d, e The interstitial tissues of mutant mice show many lymphatic spaces (arrowhead), Leydig cells (LC) with many vacuoles and lipid droplets and fibroblasts (F). f The mutant mice show few telocytes (arrowhead) and pale large macrophages (asterisk) with many metachromatic inclusions and large vacuole

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