Fig. 9 | Laboratory Investigation

Fig. 9

From: Retinoid-related orphan nuclear receptor alpha (RORα)-deficient mice display morphological testicular defects

Fig. 9

Digital colored TEM of the seminiferous tubules of both control and mutant mice. a WT mice, with the spermatocytes (SC) contained mitochondria (M) and rough endoplasmic reticulum (rER). b The cytoplasm of the spermatids (Sd) in WT mice is characterized by Golgi apparatus (G), mitochondria (M), and prominent acrosomal cap (arrowheads). c Developing spermatids (blue) in WT mice displayed conical electron-dense nucleus with few cytoplasmic residues and developing flagellar axoneme. d The spermatocytes (SC) of mutant mice display degenerated mitochondria (M), rER, many lysosomes (L), and lipid droplets (ld). e In mutant mice, the spermatids (Sd) displayed Golgi zone (G), mitochondria (M), and acrosomal cap (arrowhead) over the nucleus. f Incompletely developed sperms (blue) in mutant mice contained massive cytoplasmic residues

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