Table 1 Items that become possible using the NanoSuit method with paraffin sections

From: The NanoSuit method: a novel histological approach for examining paraffin sections in a nondestructive manner by correlative light and electron microscopy

Items become possible by NanoSuit method for paraffin sections

Easy correlative observation of light microscopic and SEM observation for commonly used glass slides

Restoring to original H&E color after SEM observation

Observation of wet/3D structure of microorganisms with high magnification

Observation of wet/3D microstructures

Identification of nucleus by gold chloride

Identification of DAB-stained area by gold chloride

Possibility of quantitative immunohistochemical diagnosis using gold particles

Analysis of elements of paraffin sections on glass slides

  1. SEM scanning electron microscopy, H&E hematoxylin and eosin, 3D three-dimensional, DAB 3,3′-diaminobenzidine
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