Fig. 1 | Laboratory Investigation

Fig. 1

From: Bone marrow mesenchymal stem cell-derived exosomal miR-144-5p improves rat ovarian function after chemotherapy-induced ovarian failure by targeting PTEN

Fig. 1

Isolation and identification of BMSCs and BMSC-derived exosomes. a Third generation BMSCs exhibited a typical fibroblastic morphology. Scale bar: 100 μm. b BMSCs differentiated into osteoblasts. Scale bar: 100 μm. c FCM analysis of BMSCs. The cells were positive for CD90 and CD105 and negative for CD34, CD45, and CD19. d Electron microscopy image of exosomes isolated from BMSC-conditioned medium. Scale bar: 200 nm. e Western blot analysis of CD9, CD81, and tubulin expression in BMSC-derived exosomes (EXO) and BMSCs

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