Fig. 2
From: Temperature elevation in epileptogenic foci exacerbates epileptic discharge through TRPV4 activation

Local brain temperature is dynamically changed in relation to brain activity. a A schematic drawing of a newly designed local temperature detection system. The picture of right black bar (red arrowhead) represents our original thermistor is very tiny compared with a commercial thermistor (left silver bar; for mouse body temperature detection, Physitemp Co. Ltd., TCAT-2DF). The two lead cables of our thermistors were connected to a 5 mm2 computer circuit board, which was also connected to our local temperature detection system. b Representative traces of local brain temperature, EEG, and EMG in WT hippocampal DGs under freely moving conditions. c: The average core body or brain (DG) temperature (n = 6 WT mice) was quantified during sleep or wakefulness. The asterisks represent statistical significance (p < 0.05) compared with the sleep period