Fig. 3
From: Temperature elevation in epileptogenic foci exacerbates epileptic discharge through TRPV4 activation
A new device for local brain cooling. a A photo showing our novel brain cooling device. The thin, black bar is surgically implanted into the mouse brain. The square, black piece is equipped with a Peltier device. To prevent heating of the Peltier device, the cooling device is equipped with four funnels. The six-pin unit is connected to a cable (as shown in panel C) for measurement of brain temperature and EEG. b Properties of our brain cooling device. After turning on the switch, the black bar (shown in A) can be immediately cooled to around 12 °C. c Appearance of the mice post-operation
