Table 1 Significantly enriched miRNA seed variants in the comparison of patient cohort with gnomAD NFE population.
From: Analysis of DNA variants in miRNAs and miRNA 3ʼUTR binding sites in female infertility patients
miRNA | Chr | Start | End | Ref | Alt | dbSNP150 | AF_Patienta | AF_gnomAD NFEa | pValb | FDRc |
|---|---|---|---|---|---|---|---|---|---|---|
hsa-mir-4472-2-5p | 12 | 116866112 | 116866114 | CA | – | rs202127912 | 0.23 | 1.60E−02 | 2.6E−54 | 1.5E−51 |
hsa-mir-8078-3p | 18 | 112284 | 112285 | G | C | 0 | 0.17 | 3.90E−02 | 2.2E−16 | 6.1E−15 |
hsa-mir-8078-3p | 18 | 112286 | 112287 | C | A | rs775697263 | 0.15 | 3.50E−02 | 4.3E−16 | 1.2E−14 |
hsa-mir-8078-3p | 18 | 112281 | 112282 | C | A | 0 | 0.04 | 1.00E−03 | 5.4E−13 | 1.2E−11 |
hsa-mir-1273a-3p | 8 | 101036233 | 101036234 | G | A | rs932668866 | 0.01 | 1.34E−04 | 1.2E−04 | 1.5E−03 |
hsa-mir-6859-1-3p | 1 | 17384 | 17385 | G | A | rs201535981 | 0.25 | 1.60E−01 | 6.1E−04 | 6.8E−03 |
hsa-mir-1273d-5p | 1 | 10287790 | 10287791 | A | G | 0 | 0.01 | 6.74E−05 | 1.6E−03 | 1.6E−02 |
hsa-mir-302c-3p | 4 | 113569539 | 113569543 | ACTT | – | rs199971565 | 0.06 | 3.00E−02 | 5.1E−03 | 4.4E−02 |
