Fig. 7: NOS2 expression and metastasis-free survival in patients with ER+ tumors. | Laboratory Investigation

Fig. 7: NOS2 expression and metastasis-free survival in patients with ER+ tumors.

From: Nitric oxide-targeted therapy inhibits stemness and increases the efficacy of tamoxifen in estrogen receptor-positive breast cancer cells

Fig. 7

Metastasis-free survival rates of ER+ breast cancer patients treated with tamoxifen or chemotherapy, according to NOS2 gene expression in their tumors. Kaplan–Meier curves were made using the on-line Kaplan–Meier plotter tool (http://kmplot.com/analysis/). All possible cut-off values between the lower and upper quartiles were computed and the best performing threshold was used as a cut-off and the levels of NOS2 expression that are below or above this threshold are considered as low or high expression, respectively.

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