Fig. 3: MiR-1246 and miR-10b-5p are increased in H-GDEs, delivered by H-GDEs and their clinical relevance. | Laboratory Investigation

Fig. 3: MiR-1246 and miR-10b-5p are increased in H-GDEs, delivered by H-GDEs and their clinical relevance.

From: Exosomes derived from hypoxic glioma deliver miR-1246 and miR-10b-5p to normoxic glioma cells to promote migration and invasion

Fig. 3

a Quantitative RT-PCR analysis of miR-1246 and miR-10b-5p expression in N-GDEs and H-GDEs from U87MG and U251 glioma cells. b Quantitative RT-PCR analysis of miR-1246 and miR-10b-5p expression in N-GDE- and H-GDE-treated U87MG and U251 glioma cells. c Expression levels of miR-1246 in LGG and GBM in CGGA database. d Expression levels of miR-10b in LGG and GBM in CGGA database. e Survival analysis for glioma patients with low and high expression of miR-1246. f Survival analysis for glioma patients with low and high expression of miR-10b. Data are shown as the mean ± SD of three independent experiments. Statistical significance was determined using Student’s t test and log-rank analysis (*P < 0.05; **P < 0.01).

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