Fig. 1: Biliatresone induced clinical manifestations of BA in neonatal mice.
From: The synthetic toxin biliatresone causes biliary atresia in mice
Survival curve (a), jaundice rate (b), clinical signs of biliary obstruction (c), and development of weight (d) in mice after biliatresone and saline injection. The body weight of mice with different outcomes at injection (e). Serum levels of ALT, AST, TB, and MMP-7 were measured in mice with persistent jaundice and controls at 14 days post injection. N = 90 and 20 samples for the biliatresone and the saline injection group, respectively. *p < 0.05, **p < 0.01, ***p < 0.001.
