Fig. 2: Retinoblastoma tumors deregulate differentiation pathways and express a robust immune-cell recruitment signature. | Laboratory Investigation

Fig. 2: Retinoblastoma tumors deregulate differentiation pathways and express a robust immune-cell recruitment signature.

From: Retinoblastoma tumor cell proliferation is negatively associated with an immune gene expression signature and increased immune cells

Fig. 2

Four thousand and transcripts identified by RNA-sequencing were log transformed, mean centered and used for hierarchical clustering of gene transcripts. Five unique clusters were identified and labeled progenitor, cell cycle, immune, mature, and differentiation to categorize them. Relative expression levels of transcripts is denoted by the blue (low) to yellow (high) color code.

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