Fig. 2: Silencing of EZH2 inhibited inflammation of epithelial cells by upregulation of FOXO3.

A EZH2 and FOXO3 determined by western blot analysis. B Inflammatory cytokines determined by ELISA. C TGF-β, MMP9, and TIMP-1 detected by western blot analysis. *p < 0.05 compared to sh-NC + sh-NC. #p < 0.05 compared to sh-EZH2 + sh-NC. Statistical comparisons were performed by Tukey’s test-corrected one-way ANOVA when more than two groups were compared.