Fig. 2: Effects of PHLDA3 expression on the proliferation and invasion of lung cancer cells.

MTS assays (A, B) and colony formation assays (C, D) for H1299 and A549 cells transfected with PHLDA3 or siRNA against PHLDA3 (siPHLDA3). E, F Images and histograms of Matrigel invasion assays of the H1299 and A549 cells transfected with PHLDA3 or siPHLDA3. G, H Images and histograms of wound healing assays of the H1299 cells transfected with PHLDA3 or siPHLDA3. NC cells transfected with empty vector, siNC cells transfected with scrambled siRNA. *p < 0.05, **p < 0.01.