Fig. 1: The most relevant clinical, imaging, and histologic parameters. | Laboratory Investigation

Fig. 1: The most relevant clinical, imaging, and histologic parameters.

From: Recombinant myelin oligodendrocyte glycoprotein quality modifies evolution of experimental autoimmune encephalitis in macaques

Fig. 1

A Mean time from onset to pic of EAE in days post-onset. B Total sum of days with clinical signs of EAE. C Number of remissions of EAE observed in each animal. D Area of brain lesions measured with MRI before euthanasia. E Cumulative severity score of observed histopathologic lesions. F Levels of anti-MOG IgG in plasma at euthanasia. MOG1 refers to animals immunized with rhMOG1 and MOG2 to animals immunized with rhMOG2. *P ≤ 0.05; ns not significant. Horizontal lines: median values of the group.

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