Fig. 2: Physical and biochemical characterization of osteosarcoma exosomes. | Laboratory Investigation

Fig. 2: Physical and biochemical characterization of osteosarcoma exosomes.

From: Development of an exosomal gene signature to detect residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning

Fig. 2

A Scanning electron micrographs of OSCA-40 exosomes. B Immunoblotting of exosome preparations documenting enrichment of tetraspanins (CD63) and depletion of β-actin in OSCA-8, OSCA-32, OSCA-40, and OSCA-78 dog osteosarcoma cell lines. C NanoSight particle tracking analysis of triplicate samples each of osteosarcoma cell lines OSCA-8, OSCA-32, OSCA-40, and OSCA-78, showing modal diameters of approximately 130 nm.

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