Fig. 3: ZKSCAN3 deficiency improved bacterial killing in lung of mice.
From: ZKSCAN3 in severe bacterial lung infection and sepsis-induced immunosuppression
A Zkscan3 genomic structure with indicated exons, FRT/loxP and loxP sites, as well as the primers used for genotyping. B The mRNA profile for indicated autophagy, phagolysosomal and lysosomal components in lungs of wild-type and ZKSCAN3−/− mice. Data normalized to the level of actin expression. Mean ± sem, n = 9, *p < 0.05 (Student’s t test). C The colony-forming units (CFUs) from lungs of wild-type and ZKSCAN3 deficient mice that were exposed to PAK (2.5 × 107; i.t.) for 4 h. Mean ± sem, n = 7 per each groups of mice, *p < 0.05 (Student’s t test).
