Fig. 4: Comparison of lung histology between wild-type and Zkscan3−/− mice.
From: ZKSCAN3 in severe bacterial lung infection and sepsis-induced immunosuppression
A Images of H&E stained lung sections from wild-type or Zkscan3−/− mice that were subjected with or without PAK (2.5 × 107; i.t.) for 4 h. Black arrows indicate spaces filled with a mixed mononuclear/neutrophilic infiltrates and cellular debris. Alveolar walls are also thickened, and the septa are edematous (blue arrows). Images of lung sections with immunostaining for (B) Rubicon or (C) ATG5 in wild-type or ZKSCAN3 deficient mice, including with or without exposure to PAK.
