Fig. 1: The expression levels of TRPC3 and NCX1 were significantly increased in DO rat bladders. | Laboratory Investigation

Fig. 1: The expression levels of TRPC3 and NCX1 were significantly increased in DO rat bladders.

From: Increased transient receptor potential canonical 3 activity is involved in the pathogenesis of detrusor overactivity by dynamic interaction with Na+/Ca2+ exchanger 1

Fig. 1

a Unlike control rats (n = 40), DO rats (n = 31) exhibited significant nonvoiding detrusor contractions before micturition. The black arrows represent nonvoiding detrusor contractions. b, c Bladder weight was significantly increased in DO rats (n = 5). d–f The mRNA (n = 9) and protein (n = 3) levels of TRPC3 and NCX1 were significantly increased in the DO bladder. g The IHC staining results demonstrated that TRPC3 (n = 3) and NCX1 (n = 3) were distributed in all layers of the bladder). **P < 0.01, ***P < 0.001.

Back to article page