Table 3 The definition of glioblastoma, IDH-wild-type, grade 4.

From: Grading of adult diffuse gliomas according to the 2021 WHO Classification of Tumors of the Central Nervous System

An IDH-wild-type, H3-wild-type, diffuse astrocytic glioma

and

One or more of the following:

• Microvascular proliferation

• Necrosis

• TERT promoter mutation

• EGFR gene amplification

• +7/−10 chromosome copy-number alterations

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