Fig. 4: Renal and hepatic cysts in a PKD1insG/+ founder cloned pig at 36 months of age. | Laboratory Investigation

Fig. 4: Renal and hepatic cysts in a PKD1insG/+ founder cloned pig at 36 months of age.

From: Generation of heterozygous PKD1 mutant pigs exhibiting early-onset renal cyst formation

Fig. 4

A Coronal section of the kidney from a PKD1insG/+ clone (K92) at 36 months of age. The bar is 3 cm. B Kidney tissue sections with Masson’s trichrome staining. Asterisks indicate renal cysts. The bar is 1 mm. C Gross morphology of the liver from the cloned pig. Hepatic cysts are indicated by yellow arrowheads. The bar is 3 cm. D, F Macroscopic cysts and their histopathological evaluation using Masson’s trichrome staining (E, G). The asterisk indicates a hepatic cyst. The bars represent 2 mm (D and F), 2.5 mm (E), and 5 mm (G).

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