Fig. 1: WISP-2 mRNA and protein constitutive expression along ATDC-5 differentiation.
From: WISP-2 modulates the induction of inflammatory mediators and cartilage catabolism in chondrocytes

A WISP-2 mRNA and protein expression along ATDC-5 differentiation after 7, 14, and 21 days. Cell lysates underwent western blot analysis using WISP-2 antibody. GAPDH was used as a loading control. Values are the mean ± SEM of at least four independent experiments (*p < 0.05, **p < 0.01 vs. control). B mRNA levels of MMP-13 along ATDC-5 differentiation. Values are the mean ± SEM of at least four independent experiments (***p < 0.001 vs. control). C Immunocytochemical images showing WISP-2 protein expression in ATDC-5 cells along cell differentiation at 0, 5, 11, 15, and 21 days.