Table 3 L1CAM and laminin expression in replacement and desmoplastic growth patterns and influence of melanin index.

From: L1CAM and laminin vascular network: Association with the high-risk replacement histopathologic growth pattern in uveal melanoma liver metastases

 

HGP (%)

 
 

Replacement

Desmoplastic

Pushing

L1CAM

Laminin

Melanin index

1

100%

  

4+

4+

0

2

100

  

4+

Inadequate*

30

3

100

  

4+

Inadequate*

180

4

85

15

 

4+

Inadequate*

0

5

100

  

2+

4+

360

6

100

  

Negative

4+

400

7

90

10

 

Negative

4+

90

8

100

  

4+

4+

140

9

100

  

4+

4+

0

10

100

  

2+

4+

240

11

100

  

Negative

4+

400

12

100

  

Negative

4+

400

13

100

  

2+

4+

160

14

100

  

4+

4+

10

15

100

  

Negative

4+

400

16

100

  

2+

Inadequate*

360

17

100

  

2+

4+

400

18

100

  

4+

4+

15

19

60

40

 

2+

4+

400

20

100

  

Negative

4+

200

21

10

65

25

Negative

Negative**

280

22

 

100

 

Negative

Negative

400

23

15

80

5

Negative

Negative

0

24

5

95

 

Negative

Negative**

280

25

5

95

 

Negative

Negative**

0

26

10

90

 

Negative

Negative**

60

27

 

100

 

Negative

Negative

400

28

15

85

 

Negative

Negative**

0

  1. *Inadequate preservation or change in fixative appears responsible for absence of laminin expressionNegative
  2. **Absence of laminin vascular network pattern in desmoplastic component, laminin vascular network pattern may be seen in focal replacement component
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