Table 1 Number of genes affected by PIK3CD knockout and their relationship with cellular and molecular functions.
Cellular function | p-value | Activation z-score | Molecules |
|---|---|---|---|
U87vsSD2 | |||
Cell movement | 1.56E-20 | −6.253 | 242 |
Migration of cells | 7.09E-18 | −5.973 | 215 |
Invasion of cells | 1.34E-09 | −3.571 | 102 |
Cell movement of tumor cell lines | 0.00000021 | −3.923 | 98 |
Chemotaxis | 0.000000834 | −3.115 | 62 |
Invasion of tumor cell lines | 0.00000117 | −3.605 | 76 |
Migration of tumor cell lines | 0.00000127 | −3.351 | 82 |
Cell spreading | 0.00000798 | −2.755 | 36 |
U87vsSD13 | |||
Cell movement | 4.26E-24 | −4.567 | 270 |
Migration of cells | 2.14E-22 | −4.725 | 244 |
Invasion of cells | 6.39E-14 | −1.943 | 122 |
Migration of tumor cell lines | 6.24E-11 | −2.336 | 102 |
Invasion of tumor cell lines | 6.16E-10 | −2.144 | 92 |
Cell movement of tumor cells | 9.35E-09 | −0.944 | 33 |
