Table 1 Summary of cytogenetic abnormalities in MGUS

From: Cytogenetic abnormalities in monoclonal gammopathy of undetermined significance

 

Heidelberg Cohort

Mayo Clinic Cohorta

Cytogenetic abnormality

n

%

n

%

t(11;14)

9/155

5.8

62/275

22.5

t(4;14)

8/155

5.2

8/275

2.9

t(14;16)

9/147

6.1

11/275

4.0

Gain 1q21

26/155

16.8

n.a.

 

Gain 5p15/5q35

27/135

20.0

n.a.

 

Gain 4p16

9/148

6.1

n.a.

 

Gain 9q34

35/153

22.9

50/275

18.2

Gain 11q23

24/155

15.5

53/275

19.3

Gain 15q22

28/153

18.3

33/275

12.0

Gain 19q13

30/154

19.5

n.a.

 

Hyperdiploidy

28/152

18.4

62/275

22.5

Del(8p21)

5/154

3.2

n.a.

 

Del(13q14)

37/155

23.9

77/275

28.0

Del(17p13)

2/155

1.3

5/275

1.8

  1. aAfter exclusion of patients with insufficient plasma cells