Fig. 3: DNMT3A mRNA expression in healthy individuals.

a Age-associated decrease of DNMT3A expression (median value depicted; *p = 0.017). b A marginal albeit not significant difference between DNMT3Awt and DNMT3Amut expression (median value depicted; p = 0.14). Statistical analysis was performed with the Mann–Whitney nonparametric test. wt wild type; mut mutant.