Table 3 DNMT3A mutation rate in bone marrow of healthy individuals vs. mice xenografts.

From: Prevalence and dynamics of clonal hematopoiesis caused by leukemia-associated mutations in elderly individuals without hematologic disorders

 

Individual A

Mice xenografts (8 months after transplantation)

  

Mouse A1

Mouse A2

Mouse A3

DNMT3Amut (S837X)

VAF (%)

23.1

23.8

10.8

30.8

 

Individual B

Mice xenografts (8 months after transplantation)

  

Mouse B1

Mouse B2

Mouse B3

DNMT3Amut (D768H)

VAF (%)

6.3

6.2

0

0

  1. VAF variant allele frequency.