Table 1 Association of continuous NEDD9 expression with clinical features at baseline in CLL8 cohort.

From: The scaffold protein NEDD9 is necessary for leukemia-cell migration and disease progression in a mouse model of chronic lymphocytic leukemia

Patient characteristic at baseline

Categories

N

Median NEDD9 expression

P value

All patients

337

6.421

 

Leukocyte count ≥ 50.0 × 109/L

No

83

6.263

<0.001

Yes

247

6.469

Lymph nodes > 5 cm

No

140

6.367

0.952

Yes

38

6.359

Lymph nodes > 10 cm

No

166

6.370

0.483

Yes

12

6.327

Splenomegaly > 15 cm

No

58

6.343

0.204

Yes

45

6.497

Splenomegaly > 20 cm

No

90

6.359

0.275

Yes

13

6.505

  1. Correlations between continuous NEDD9 expression and leukocyte count, enlargement of lymph nodes, and splenomegaly at baseline time point were evaluated using Mann–Whitney U test. The analyses of lymph node and spleen sizes refer only to patients with measurements via CT scan. A p-value of <0.05 was defined as significant (bold value). No adjustments for multiple testing were done. The analyses were performed using SPSS 27.0.
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