Fig. 3: AEA measurements and 95% CI over time in the groups; Allergic reaction on 3^rd dose, 4^th dose, and 5^th dose compared to no inactivation.

AEA measurements day 1,4,7 and 11 after first dose and AEA C_trough after every dose of peg-asparaginase for patients <16 years (IV administration). Patients without inactivation are shown in red, those experiencing allergic reactions on the 3^rd dose in blue, on the 4^th dose in green, and on the 5^th dose in black.