Table 3 Follow-up data after pregnancy completion in 87 CML patients.

From: Chronic myeloid leukemia diagnosed in pregnancy: management and outcome of 87 patients reported to the European LeukemiaNet international registry

Follow-up data

All patients

Pregnancy outcome

n = 87

Childbirth

Abortion/miscarriage

 

n = 66

n = 21

Living status

   

 Alive, n (%)

84 (97)

64 (97)

20 (95)

 Dead, n (%)

3 (3)

2 (3)

1 (5)

First line TKI

   

 Imatinib, n(%)

71 (82)

51 (77)

20 (95)

 Dasatinib, n (%)

9 (10)

9 (14)

–

 Nilotinib, n (%)

7 (8)

6 (9)

1 (5)

TKI switch, main reason

   

 Resistance/suboptimal, n (%)

18 (21)

14 (21)

4 (19)

 Intolerance/other, n (%)

6 (7)

4 (6)

2 (10)

 No switch, n (%)

63 (72)

48(73)

15 (71)

Best overall response, n (%)

   

 MMR

28 (32)

22 (33)

6 (29)

 DMR

38 (44)

31 (47)

7 (33)

 No MMR

12 (14)

8 (12)

4 (19)

 No data

9 (10)

5 (8)

4 (19)

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