Table 1 Clinical characteristics.
PMBCL (N = 70) | Other LBCL (N = 190) | p value | |
|---|---|---|---|
Sex | 0.0312 | ||
Female | 34 (49%) | 64 (34%) | |
Male | 36 (51%) | 126 (66%) | |
Age | 0.0001 | ||
Mean (SD) | 35.0 (11.4) | 55.9 (12.3) | |
Median [Q1, Q3] | 33.0 [27.0, 41.8] | 57.5 [50.0, 65.0] | |
Disease status | 0.0048 | ||
Refractory | 63 (90.0%) | 141 (74%) | |
Relapse | 6 (9%) | 46 (22%) | |
Missing | 1 (1%) | 3 (2%) | |
Ann Arbor | 0.0001 | ||
I–II | 43 (61%) | 64 (34%) | |
III–IV | 27 (39%) | 126 (66%) | |
LDH | 0.0958 | ||
Mean (SD) | 255 (243) | 344 (574) | |
Median [Q1, Q3] | 190 [154, 264] | 203 [167, 314] | |
Missing | 4 (6%) | 8 (4%) | |
IPI | 0.0078 | ||
<3 | 55 (79%) | 113 (59%) | |
≥3 | 15 (21%) | 74 (39%) | |
Missing | 0 | 3 (2%) | |
Bulky disease | 0.0015 | ||
No | 29 (42%) | 122 (64%) | |
Yes | 40 (57%) | 66 (35%) | |
Missing | 1 (1%) | 2 (1%) | |
Number of previous treatments | 0.3055 | ||
Mean (SD) | 2.60 (0.858) | 2.49 (0.832) | |
Median [Q1, Q3] | 2 [2, 3] | 2 [2, 3] | |
Missing | 0 | 3 (2%) | |
Previous ASCT | 0.0778 | ||
No | 58 (83%) | 136 (72%) | |
Yes | 12 (17%) | 54 (28%) |