Fig. 2: UMAP analysis of the 300 CpGs in germinal center-derived B-cell lymphomas.

UMAP analysis based on 300 CpGs identified by PGMRA, using Manhattan distance and 15 neighbors. The UMAP plots are colored according to various features: lymphoma classification, median DNA methylation levels, methylation patterns (MPs) and tumor cell content based on whole genome sequencing. FL Follicular lymphoma, DLBCL Diffuse large B-cell lymphoma.