Fig. 1: Prognostic relevance of LSC status at diagnosis, using a cutoff of 0.01% of WBC and after three cycles of therapy, using a cutoff of 0.001% of WBC.

A Overall survival (OS) based on LSC status at diagnosis. B Cumulative incidence of relapse (CIR) based on LSC status at diagnosis from the time of first CR. C Multivariable Cox regression of the overall survival from diagnosis for LSC status at diagnosis. D Overall survival based on LSC status after three cycles from the time of sampling. E Cumulative incidence of relapse for patients reaching CR/CRi/MLFS from time of sampling based on LSC status after three cycles F Multivariable Cox regression for overall survival for LSC status after three cycles (C3).