Fig. 2: IKAROS recruits and activates EZH2. | Leukemia

Fig. 2: IKAROS recruits and activates EZH2.

From: Critical roles of IKAROS and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemia

Fig. 2

A Heatmaps of EZH2 and H3K27me3 ChIP-seq signals in IKAROS-null T-ALL. B, C Heatmaps of EZH2, IKAROS and H3K27me3 ChIP-seq signals in IKAROS-EZH2 occupied (B), and EZH2-only occupied (C) regions. D EZH2-only and EZH2-IKAROS occupied sites classified by function of the DNA element. E, F Gene ontology and pathway enrichment analysis of genes associated with EZH2-IKAROS complexes.

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