Fig. 7: IKAROS regulates genomic occupancy and distribution of EZH2 and HDAC1 and H3K27me3 formation in human T-ALL. | Leukemia

Fig. 7: IKAROS regulates genomic occupancy and distribution of EZH2 and HDAC1 and H3K27me3 formation in human T-ALL.

From: Critical roles of IKAROS and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemia

Fig. 7

A Number of H3K27me3 (left) and HDAC1 (right) peaks in wildtype MOLT-4 and in IKZF1-knockout (MOLT-IK-KO) cells. B H3K27me3 and HDAC1 occupied sites, in wildtype MOLT-4 and in IKZF1-knockout (MOLT-IK-KO) cells, classified by function of the DNA element. C, D Gene ontology and pathway enrichment analysis of genes associated with HDAC1 occupancy in wildtype MOLT-4 cells.

Back to article page