Table 1 Clinical Spectrum of Solitary Plasmacytomas [2,3,4, 6].

From: Solitary but not simple─a call for precision risk stratification and individualized treatment in solitary plasmacytoma

Entity

Definition

3-year progression-free survivala

Solitary Bone Plasmacytoma

Presence of a solitary bone-associated lesion with clonal plasma cell infiltrate without evidence of clonal BMPCs.

64–94%

Solitary Bone Plasmacytoma with Minimal Marrow Involvement

Presence of solitary bone-associated lesion with clonal plasma cell infiltrate and presence of less than 10% clonal BMPC infiltrate.

28–37%

Solitary Extramedullary Plasmacytoma

Presence of solitary soft tissue/visceral clonal plasma cell infiltrate with no evidence of clonal BMPC infiltrate.

85–94%

Solitary Extramedullary Plasmacytoma with Minimal Marrow Involvement

Presence of solitary soft tissue/visceral clonal plasma cell infiltrate and presence of less than 10% clonal BMPC infiltrate.

56-80%

Multiple Myeloma

Presence of solitary bone-associated or extramedullary plasmacytoma and ≥10% clonal BMPC infiltrate

Not Applicable

  1. aProgression to multiple myeloma or recurrence of solitary bone/extramedullary plasmacytoma, with approximate ranges derived from key selected studies. BMPCs bone marrow plasma cells.
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