Fig. 3: Results from the comparison of gene expression patterns between patients with Erdheim–Chester disease and controls. | Leukemia

Fig. 3: Results from the comparison of gene expression patterns between patients with Erdheim–Chester disease and controls.

From: Unraveling the molecular landscape of Erdheim–Chester disease: new insights from methylome and transcriptome integration

Fig. 3

A Volcano plot of the transcriptomic study results. False discovery rate (FDR) values are represented on the –log10 scale in the y-axis. The effect size and direction obtained for each gene is depicted in the x-axis though the log fold change (logFC) value. Orange and blue dots represent upregulated and downregulated differentially expressed genes (DEGs), respectively. B Results of the Gene Ontology (GO) enrichment analysis of DEGs. Most relevant terms are displayed in the plot. The colours of the bars represent the different groups in which the GO terms were classified.

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