Table 2 Clinical data stratified by clinical trial.

From: The endogenous T cell landscape is reshaped by CAR-T cell therapy and predicts treatment response in multiple myeloma

 

Total (n = 24)

KarMMa-3 (n = 17)

KarMMa-2 (n = 7)

p-value

Age (years, mean, SD)

61.0 (9.87)

61.1 (9.63)

61.0 (11.0)

0.9825

Sex (m / f, n, %)

18 (75%) / 6 (25%)

13 (76%) / 4 (24%)

5 (71%) / 2 (29%)

0.7954

Ethnicity (white, black or African American, n, %)

21 (87.5%) / 3 (12.5%)

15 (88%) / 2 (12%)

6 (86%) / 1 (14%)

0.8652

Best Overall Response

Stringent complete response

12 (50%)

8 (47.1%)

4 (57.1%)

0.2825

Complete response

2 (8.8%)

1 (5.9%)

1 (14.3%)

 

Very good partial response

4 (16.7%)

4 (23.5%)

0 (0%)

 

Partial response

2 (8.3%)

1 (5.9%)

1 (14.3%)

 

Minimal response

1 (4.2%)

0 (0%)

1 (14.3%)

 

Stable disease

3 (12.5%)

3 (17.6%)

0 (0%)

 

Progression Free Survival (months, mean, SD)

18.9 (10.4)

19.2 (11.5)

18.4 (8.3)

0.8696