Table 1 Study and Baseline Characteristics.
Median Age at First Diagnosis (y) (range) | History of Thrombosis at any time (n, %) | Frequency of ET (n, %) | Frequency of PV (n, %) | Frequency of PMF (n, %) | Frequency of MPN-U (n, %) | Frequency of JAK2 (n, %) | Frequency of CALR (n, %) | Frequency of MPL (n, %) | |
|---|---|---|---|---|---|---|---|---|---|
Group 1: Ph-negative MPN preceding CML 31/61 (50.8%) | 59 (19–84) | 6 (19.4%) | 12 (38.7%) | 9 (29.0%) | 9 (29.0%) | 1 (3.2%) | 22 (75.9%) | 5 (17.2%) | 2 (6.9%) |
Group 2: CML preceding Ph-negative MPN 18/61 (29.5%) | 55 (34–81) | 3 (16.7%) | 8 (44.4%) | 6 (33.3) | 1 (5.6%) | 3 (16.7%) | 16 (88.9%) | 2 (11.1%) | 0 |
Group 3: Ph-negative MPN and CML diagnosed simultaneously 12/61 (19.7%) | 57 (42–79) | 3 (25.0%) | 6 (50.0%) | 1 (8.3%) | 1 (8.3%) | 4 (33.3%) | 10 (83.3%) | 1 (8.3%) | 1 (8.3%) |
Overall cohort (n = 61) | 57 (19–84) | 12 (19.7%) | 26 (42.6%) | 16 (26.2%) | 11 (18.0%) | 8 (13.1%) | 48 (81.4%) | 8 (13.6%) | 3 (5.0%) |
