Scheme 1: Synthesis of MTP1, MTA1, MTP2 and MTA2.
From: Membrane-targeted push-pull azobenzenes for the optical modulation of membrane potential
a K2CO3 and 1,6-dibromohexane, CH3CN, 60 °C, 120 h, Ar; b Pyridine, room temperature, 120 h; c TMA, EtOH, 80 °C, 48 h; d 1,6-dibromohexane, 95 °C, 10 h, Ar; e BF3·EtOH and (CH3)3CONO, THF, −20 °C, 1 h; f CH3CN, 5 °C, 3 h; g Pyridine, room temperature, 24 h; h TMA, EtOH, 80 °C, 48 h
