Fig. 3: Ex vivo zebrafish heart volumetric imaging and the corresponding restorations using UI-Trans, CARE and RCAN.

a 3D visualizations via surface blend method of a whole zebrafish heart acquired with low-quality LSFM (input), high-quality confocal LS-LSFM (GT) and the restored results using CARE, RCAN and UI-Trans. b 2D slice images in x-y plane and zoomed-in images in the ROI (white rectangle). c 2D slice images in x-z plane. d Cross-sectional intensity profile derived from the white lines in b. e NRMSE and Pearson coefficient calculated from the output restored images. Scale bars: 50 μm