Fig. 1 | Modern Pathology

Fig. 1

From: TERT promoter mutation in adult granulosa cell tumor of the ovary

Fig. 1

a TERT promoter mutation in adult granulosa cell tumors. Shown is the schematic diagram of the TERT promoter region, representative chromatograms of the two hot-spot mutations (C228T; C250T). b Mutation status of TERT C228T promoter in adult granulosa cell tumors separated by the country in which they were collected from: dark gray, TERT C228T mutated promoter; light gray, TERT wild-type promoter. c Adult granulosa cell tumors with mutated TERT promoter have increased expression of TERT mRNA; black horizontal bar, mean. d Comparison of XpYp STELA telomere length mean between adult granulosa cell tumors with and without TERT promoter mutation; black horizontal bar, group mean

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