Table 4 Tumors with >50% IDO expression
Case | Age at diagnosis | Stage | Grade and histology | IDO expression | PD-L1 expression | MMR status |
|---|---|---|---|---|---|---|
1 | 44 | IIIC2 | Grade 1 endometrioid | Tumor: >50% immune: 6–10% | Tumor: 6–10% immune: 11–25% | MSH2/6 loss, confirmed MSH2 mutation |
2 | 57 | IIIA | Grade 1 endometrioid | Tumor: >50% immune: 1–5% | Tumor: 1–5% immune: 6–10% | PMS2 loss, germ line untested |
3 | 39 | IA | Grade 2 endometrioid | Tumor: >50% immune: 1–5% | Tumor: 1–5% immune: 1–5% | PMS2 loss, confirmed PMS2 mutation |
4 | 79 | IB | Grade 2 endometrioid | Tumor: >50% immune: 1–5% | Tumor: <1% immune: 26–50% | MLH1/PMS2 loss, MLH1 methylation |
