Table 4 Univariate analysis for OS and DSS of adenocarcinomas with H-FLAC

From: Pulmonary adenocarcinoma with high-grade fetal adenocarcinoma component has a poor prognosis, comparable to that of micropapillary adenocarcinoma

 

Number

5-yr OS (%)

P value

5-yr DSS (%)

P value

Age (years)

  ≤65

17

47

0.796

76

0.360

  >65

24

51

 

56

 

Sex

  Female

9

75

0.548

75

0.866

  Male

32

39

 

56

 

Smoking

  Never

4

NA

0.422

NA

0.175

  Ever

31

42

 

61

 

Tumor size (mm)

  ≤30

17

48

0.353

59

0.466

  >30

24

50

 

68

 

Pleural invasion

  Absent

20

64

0.138

87

0.056

  Present

21

39

 

46

 

Lymphovascular invasion

  Absent

14

65

0.752

82

0.487

  Present

27

47

 

60

 

Stage

  I

23

69

0.002

77

0.023

  II

9

43

 

58

 

  III

9

NA

 

NA

 

Proportion of H-FLAC component

  Predominant (≥50%)

25

44

0.962

63

0.545

  Non-predominant (<50%)

16

56

 

64

 

Solid/micropapillary patterns

  Absent

17

23

0.749

26

0.331

  Present

24

56

 

77

 
  1. OS overall survival, DSS disease-specific survival, H-FLAC high-grade fetal adenocarcinoma of the lung, NA not applicable