Table 5 Clinicopathological features of adenocarcinomas with H-FLAC and major subtypes of lung adenocarcinoma

From: Pulmonary adenocarcinoma with high-grade fetal adenocarcinoma component has a poor prognosis, comparable to that of micropapillary adenocarcinoma

 

Total

Adenocarcinomas with H-FLAC

Lepidic

Acinar

Papillary

Solid

Micropapillary

Invasive mucinous

Number

1550

36

447

442

309

204

29

83

Age (year)

  Median

68

67

69

68

67

66

68

72

  Range

29–93

47–87

36–86

35–90

35–88

29–82

38–83

32–85

Sex

  Female

758

8

244

230

158

60

10

48

  Male

792

28

203

212

151

144

19

35

Smoking

  Never

705

5

249

214

137

47

10

43

  Ever

832

30

192

226

170

155

19

40

  No data

13

1

6

2

2

2

0

0

Tumor size (mm)

  Median

28

36

27

26

28

28

33

32

  Range

7–210

17–122

7–120

7–160

8–90

8–102

14–62

10–210

Pleural invasion

  Absent

1120

15

405

306

199

103

18

74

  Present

430

21

42

136

110

101

11

9

Lymphovascular invasion

  Absent

888

11

390

236

129

44

6

72

  Present

662

25

57

206

180

160

23

11

Stage

  I

1112

19

415

324

180

109

13

52

  II

245

9

23

60

72

49

5

27

  III

187

8

9

57

57

41

11

4

  IV

6

0

0

1

0

5

0

0

  1. H-FLAC high-grade fetal adenocarcinoma of the lung