Table 1 Clinical and demographic data of polyoma T-antigen-expressing urologic carcinomas

From: Polyoma virus-associated carcinomas of the urologic tract: a clinicopathologic and molecular study

Case #

Age

Sex

Cancer risk factors

Time since TX

BK viremia

TX/immunosupressed state

Underlying disease

Tumor pathology

Stage

Follow up duration (months)

Follow up

1

56

M

Non-smoker

10 years

7 years

Heart and renal TX, second heart TX

Ischemic CMP

HGUC

pT3Nx

7

Recurrence X 3, Metastasis to pleural fluid. DOD

2

66

F

Smoker

8 years

N/A

Heart TX

Ischemic CMP

HGUC

pT4aN2

3

Recurrence x2, AWD

3

69

M

N/A

6 years

N/A

Heart and renal TX

Ischemic CMP

CDC, incidental finding at autopsy

pT1aN0

N/A

Died of unrelated causes

4

41

F

N/A

4 years

N/A

Renal TX

ADPKD

CDC

pT3

N/A

N/A

5

80

M

Non-smoker, painter

10 years

N/A

Steroid therapy

Colon cancer, bullous pemphigoid, diabetes mellitus

HGPUC

pTIS

21

Recurrent disease, localized

6

79

M

N/A

7 years

2 years

Heart TX, second heart and renal TX

Ischemic CMP

HGUC upper renal calyx

pT3Nx

1

AWD

7

37

F

Non-smoker

11 years

10 years

Renal TX

ESRD secondary to reflux nephropathy

HGUC

pT4aN1MX

13

No recurrence

8

53

M

N/A

1 year

Negative

Renal TX x 3

ESRD secondary to hypertension

HGUC

pT3aN0MX

22

Death of “pelvic mass” not diagnostically proven

9

69

M

N/A

11 years

3 years 

Renal TX

IgA nephropathy

HGUC

pT3aNxMx

12

Metastasis to aortic lymph nodes, dialysis dependent

10

42

M

N/A

3 years

N/A

Renal TX

Diabetic ESRD

HGUC

pT3aNxMx

132

AWD

11

68

F

 N/A

6 years

6 years

Renal TX

ESRD s/p bilateral ureteral strictures

HGPUC

 pT2aN0Mx

9

 No recurrence

  1. AWD alive with disease, ADPKD autosomal dominant polycystic kidney disease, CMP cardiomyopathy, CDC collecting duct carcinoma, DOD dead of disease, ESRD nd stage renal disease, F female, HGPUC high-grade papillary urothelial carcinoma, HGUC high-grade urothelial carcinoma, N/A not available, M male, TX transplant