Table 1 Clinicopathologic features of metaplastic carcinomas

From: Genomic profiling of metaplastic breast carcinomas reveals genetic heterogeneity and relationship to ductal carcinoma

Case

Age/gender

Differentiation

Size (cm)

Grade

ER/PR/HER2

DCIS

DCIS grade/pattern

Lymph nodes

Distant mets

Sp1

82/F

Spindle

3

3

−/−/−

Yes

Intermediate/micropapillary, papillary, cribriform

0/2

No

Sp2

85/F

Spindle

4.8

2

−/−/−

No

NA

No

Sp3

67/F

Spindle

2.5

2

−/−/−

No

0/1

No

Sp4

45/F

Spindle

11.4/12b

3

−/−/−

No

4/41

Noc

Sp5

56/F

Spindle

2.3

3

−/−/−

Yes

Highd/solid, cribriform, comedo

0/3

No

SS1

61/F

Squamous and spindle

10

3

−/−/−

No

0/4

No

SS2

79/F

Squamous and spindle

6.3

3

−/−/−

No

NA

NA

SS3

82/F

Squamous and spindle

1.4

3

−/−/−

Yes

High/ solid, cribriform, comedo

1/4

No

SS4

60/F

Squamous and spindle

6.4/1.6b

3

−/−/+

Yes

High/solid

1/15

No

SS5

57/F

Squamous and spindle

2.2

3

−/−/−

No

1/14

No

Sq1

64/F

Squamous

13/12b

3

−/−/−

Yes

High/solid

9/16

No

Sq2

69/F

Squamousa

5.1

3

−/−/−

Yes

High/micropapillary, comedo

2/49

No

Sq3

63/F

Squamous

4.4

3

−/−/−

Yes

High/solid, micropapillary, comedo

0/1

No

Sq4

65/F

Squamousa

6.6

3

−/−/−

Yes

High/solid, comedo

0/4

No

Sq5

54/F

Squamousa

3.2

3

+/−/−

Yes

High/solid and comedo

0/2

No

C1

71/F

Chondroida

2

3

−/−/−

No

0/1

No

C2

45/F

Chondroida

3/1.7b

3

−/−/−

No

1/7

No

C3

52/F

Chondroida

4.7

3

−/−/−

No

3/9

No

C4

78/F

Chondroida

1.4

3

−/−/−

No

0/1

No

C5

25/F

Chondroida

2.5

3

−/−/−

No

0/7

No

C6

42/F

Chondroida

1.8

3

−/−/−

Yes

High/solid, comedo

0/1

No

C7

26/F

Chondroida

2.7/4.8b

3

−/−/−

No

0/1

No

C8

75/F

Chondroida

1.5

3

−/−/−

No

0/3

No

C9

73/F

Chondroida

4

3

−/−/−

Yes

Intermediate/solid

0/2

No

C10

74/F

Chondroid, focal osseousa

0.9

3

−/−/−

Yes

High/solid

0/1

No

M1

70/F

Spindle, squamous, osseous

6

3

−/−/−

No

0/1

Lung, (osseous)

M2

46/F

Spindle, osseous, chondroid, rhabdomyoida

NA/16.5b

3

−/−/−

No

2/6

Intercostal

M3

50/F

Squamous, chondroid, osseous, spindlea

2.7/10b

3

−/−/−

No

0/8

Lung (squamous)

  1. aAlso with ductal component
  2. bImaging size before neoadjuvant chemotherapy/pathologic size after neoadjuvant chemotherapy
  3. cLocal chest wall recurrence
  4. dApocrine ductal carcinoma in situ