Table 1 Characteristics of primary tumors according to tissue-obtained metastatic sites
| Â | Tissue-obtained metastatic sites | |||
|---|---|---|---|---|
Lung (%) | Liver (%) | Brain (%) | Ovary (%) | |
Histological type | ||||
  DCIS | 2 (1) | 1 (1) | 0 (0) | 0 (0) |
  IDC | 158 (99) | 94 (97) | 52 (98) | 23 (92) |
  ILC | 0 (0) | 1 (1) | 1 (2) | 2 (8) |
  Mucinous carcinoma | 0 (0) | 1 (1) | 0 (0) | 0 (0) |
Histological grade | ||||
  1 | 4 (3) | 1 (1) | 0 (0) | 0 (0) |
  2 | 63 (39) | 47 (49) | 14 (26) | 18 (72) |
  3 | 70 (44) | 33 (34) | 35 (66) | 5 (20) |
   Unknown | 23 (14) | 16 (16) | 4 (8) | 2 (8) |
Hormone receptor | ||||
  Negative | 57 (36) | 29 (30) | 28 (53) | 2 (8) |
  Positive | 90 (56) | 62 (64) | 23 (43) | 23 (92) |
  Unknown | 13 (8) | 6 (6) | 2 (4) | 0 (0) |
HER2 | ||||
  Negative | 97 (61) | 52 (54) | 21 (40) | 21 (84) |
  Positive | 41 (26) | 31 (32) | 29 (55) | 4 (16) |
  Unknown | 22 (14) | 14 (14) | 3 (5) | 0 (0) |
Subtype | ||||
  HR+/HER2− | 61 (38) | 42 (43) | 10 (19) | 19 (76) |
  HR+/HER2+ | 22 (14) | 12 (12) | 13 (25) | 4 (16) |
  HR−/HER2+ | 19 (12) | 19 (20) | 15 (28) | 0 (0) |
  TN | 36 (22) | 10 (10) | 11 (21) | 2 (8) |
  Unknown | 22 (14) | 14 (15) | 4 (7) | 0 (0) |
TIL (%, median) | 2 | 3.5 | 5 | 2 |
TLS | ||||
  Absent | 52 (32) | 42 (43) | 18 (34) | 21 (84) |
  Present | 60 (38) | 26 (27) | 23 (43) | 3 (12) |
  Unknown | 48 (30) | 29 (30) | 12 (23) | 1 (4) |
