Table 6 Gene rearrangements in round cell sarcomas

From: Limited biopsies of soft tissue tumors: the contemporary role of immunohistochemistry and molecular diagnostics

Tumor type

Gene fusions

Ewing sarcoma

EWSR1-FLI1, EWSR1-ERG, others

CIC-rearranged sarcoma

CIC-DUX4

BCOR-rearranged sarcoma

BCOR-CCNB3

Alveolar rhabdomyosarcoma

PAX3-FOXO1, PAX7-FOXO1

Desmoplastic small round cell tumor

EWSR1-WT1

Poorly differentiated synovial sarcoma

SS18-SSX1, SS18-SSX2

Myxoid (“round cell”) liposarcoma

FUS-DDIT3, EWSR1-DDIT3